Related Papers
Journal of Drug Delivery and Therapeutics
A Review on Niosomes: Potential Vesicular Drug Delivery System
sweta S KOKA
Over the years researchers have been making an attempt to improve the potency of utilization of medicament for treatment of numerous diseases. During this endeavour, drug delivery systems have helped greatly by achieving reduced dose, reduced dosage frequency, improved patient compliance, improved bioavailability and maximum concentration of the drug at the target site. Recent years have seen an unprecedented growth in the use of nanotechnology in designing drug delivery systems. Niosomes are vesicles composed of non-ionic surfactants, which are biodegradable, comparatively non-toxic, stable, economical and effective alternate to liposomes. This review is deepening and widening the interest of Niosomes in several scientific disciplines and notably its application in drug delivery. This review additionally presents a summary of the types, methods of preparation, characterization and applications of Niosomes. Keywords: Niosomes, types, method of preparation, factors affecting and app...
Niosomes : as novel vesicular drug delivery system
2018 •
Sudhir Ray
Target-specific drug-delivery systems for the administration of pharmaceutical compounds enable the localization of drugs to target sites within the body. The basic component of drug delivery systems is an appropriate carrier that protects the drug from rapid degradation or clearance and thereby enhances drug concentration in target tissues. Niosome are microscopic non-ionic surfactant bilayer vesicles obtained on hydration of synthetic nonionic surfactants, with or without incorporation of cholesterol or their lipids. The amphiphilic nature of niosomes promotes their efficiency in encapsulating lipophilic or hydrophilic drugs. Noisome are promising vehicle for drug delivery and being non-ionic, more stable, inexpensive, biodegradable, biocompatible, non immunogenic and exhibit flexibility in their structural characterization. Various additives in niosomes include nonionic surfactant as film forming agent, cholesterol as stabilizing and rigidizing agent for the bilayer and various c...
Pharma Science Monitor 8(4), Oct-Dec 2017 NIOSOMES AS PROMISING VEHICLE FOR NOVEL DRUG DELIVERY SYSTEM: RECENT REVIEW
mittal kela
Niosomes are non-ionic surfactant vesicles obtained on hydration of synthetic nonionic surfactants, with or without incorporation of cholesterol or other lipids. They are vesicular systems similar to liposomes that can be used as carriers of amphiphilic and lipophilic drugs. Niosomes are promising vehicle for drug delivery and being non-ionic, it is less toxic and improves the therapeutic index of drug by restricting its action to target cells. This systemic review article deals with preparation methods, characterizations, factors affecting release kinetic, advantages, and applications of niosomes.
Journal of Advanced …
Niosome: A future of targeted drug delivery systems
2010 •
Arijit Guha
A Novel Drug Delivery System: Niosomes Review
IOSR Journals
Drug targeting is a kind of mechanism in which the drug is administered in the body in such a way that the drug interacts at a cellular or subcellular level with the target tissue to achieve a desired therapeutic response at a desired location without unwanted interactions at other sites. This can be done by modern methods such as niosomes, which target the drug delivery system. Niosomes are the type of non-ionic surfactant vesicles which are a new approach to liposomes that is biodegradable, non-toxic, more durable and cheaper. Their liposome-like structure and therefore they can represent alternate vesicular structures in relation to liposomes. The niosomes appear to load various types of drugs. This review article describes niosome structure, benefits, drawbacks, niosome preparation methods and pharmaceutical NSV characterisation.
IJRDO-Journal of Applied Science
Pharmaceutical Niosomes Drug Delivery: A Complete Review of New Delivery System
priyanka maurya
Over the past ten years, people working in the field of drug delivery systems have become increasingly interested in designing vesicles as a tool to improve drug delivery. A hydrating mixture of cholesterol and nonionic surfactants forms niosomes, which are vesicles. Liposomes, microspheres, engineering science,small emulsions, antibody loaded drug delivery , magnetic microcapsules,implantable pumps, and niosomes are just a few of the unique methods employed to administer these medications. There are two requirements before designing and developing a novel drug delivery system (NDDS). It must first spread the medication at a preset rate and then release an amount of medication at the site of action that is therapeutically efficacious. These requirements cannot be satisfied by conventional dose forms. In essence, niosomes are non-ionic surfactant-based vesicles in which a group of surfactant macromolecules forms a bilayer to form a membrane that entirely seals off an aqueous solut...
Niosomes: an excellent tool for drug delivery
IJRPP Journal
Advances in Colloid and Interface Science
Niosomes from 80s to present: The state of the art
2014 •
Donatella Paolino, Luisa Di Marzio, Christian Celia, Maria Carafa
Progress In The Field Of Niosomes As Novel Drug Delivery System
2018 •
Kaur Manpreet
Niosomes are novel drug delivery system that are having bilayer in structure and these vesicles are obtained during hydration of synthetic non-ionic surfactants, with the incorporation of cholesterol or their lipids. These vesicles present convenient, prolonged, targeted and effective drug delivery system with the ability of loading both hydrophilic and lipophilic drugs. The hydrophilic drugs are entrapped into aqueous core while the lipophilic drugs into the lipid membrane. Their potential can be enhanced by the use of novel preparations, loading and modification methods. This article reviews the current deepening and widening of interest of niosomes. Keywords: Introduction, Method of preparation, Marketed formulation, Patent citations, Opportunities and Challenges.
Niosome: An Unique Drug Delivery System
Avinash Seth
Niosomes are non-ionic surfactant vesicles obtained on hydration of synthetic nonionic surfactants, with or without incorporation of cholesterol or other lipids. They are vesicular systems similar to liposomes that can be used as carriers of amphiphilic and lipophilic drugs. Niosomes are promising vehicle for drug delivery and being non-ionic, it is less toxic and improves the therapeutic index of drug by restricting its action to target cells. This systemic review article deals with preparation methods, characterizations, factors affecting release kinetic, advantages, and applications of niosomes.
