Multimode Microplate Reader with Advanced Detection Capabilities
- Luminescence, fluorescence, UV-visible absorbance, BRET and FRET detection
- 6- to 384-well microplate reader
- Optimized with Promega cell viability and genetic reporter assays
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GloMax® Discover Microplate Reader
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Easy-to-Use Plate Reader
GloMax® Discover is a ready-to-use multimode plate reader developed with Promega reagent chemistries to provide a simple means of detecting luminescence, fluorescence and absorbance.
- High-performance luminescence, fluorescence, UV-Visible absorbance, BRET and FRET, two-color filtered luminescence and kinetic measurement capabilities
- Can be used as a standalone plate reader or integrated into high-throughput automated workflows
- Integrated data analysis software makes results easy to interpret
![GloMax® Discover Microplate Reader (4) GloMax® Discover Microplate Reader (4)](https://i0.wp.com/scv10mr-cdnpre-p-cus-00.azureedge.net/-/media/images/products/fluorometers-luminometers-multimode-readers/multimode-readers/glomax-discover/gm3000-microplate-reader-luminescence-detection.png?rev=1002e01f12ae4f06bd09c8af2c0696cc&sc_lang=it-it)
Preloaded Protocols for Faster, Easier Data Analysis
GloMax® plate readers have high sensitivity and a wide dynamic range, so you can detect both high and low signals on the same plate and have confidence in the accuracy of the signal recorded from each well. These instruments provide a range of options for your throughput needs and are equipped with integrated software that makes data analysis easy. GloMax® instruments come preloaded with protocols designed to work seamlessly with a wide variety of Promega luminescent and fluorescence-based assays at the touch of a button.
GloMax® Instruments Come with Dozens of Preloaded Protocols
See every preloaded protocol for each GloMax® instrument
GloMax® Application Notes
No need to reinvent the wheel—we’ve already used GloMax® instruments for everything from cell viability, toxicity and metabolism, kinase and cell signaling, reporter gene assays, nucleic acid quantitation for NGS sequencing, PROTACs and protein degradation, bioassays, BRET, ELISAs and even water quality testing. Search our Application Notes collection for examples using GloMax® instruments with a wide range of bioluminescence- and fluorescence-based assays.
![GloMax® Discover Microplate Reader (10) GloMax® Discover Microplate Reader (10)](https://i0.wp.com/scv10mr-cdnpre-p-cus-00.azureedge.net/-/media/images/products/reporter-assays-and-transfection/reporter-assays/nanodlr-dual-luciferase-assay/glomax-discover-system-multimode-plate-reader.png?rev=8c59f2f2a6074c798cb2b8fb39a25549&sc_lang=it-it)
Microplate Reader Performance
GloMax® Discover multimode microplate reader delivers maximum flexibility with minimal user intervention and can be integrated into low- and medium-throughput automation workflows. The instrument provides superior luminescence sensitivity and dynamic range for both strong and weak bioluminescence experimental samples, as well as seamless integration with Promega bioluminescent cell and gene reporter assays.
![GloMax® Discover Microplate Reader (11) GloMax® Discover Microplate Reader (11)](https://i0.wp.com/scv10mr-cdnpre-p-cus-00.azureedge.net/-/media/images/products/fluorometers-luminometers-multimode-readers/multimode-readers/glomax-discover/gm3000-glomax-multimode-microplate-reader.jpg?rev=21bfa277c2bf4285ba9e177ae3cdc559&sc_lang=it-it)
- Simple touch-screen navigation with full PC capabilities
- Choose from over 50 preloaded protocols, and spend less time optimizing
- Build custom protocols using the intuitive drag-and-drop interface
- Export data to a network, cloud or any desired drive
![GloMax® Discover Microplate Reader (12) GloMax® Discover Microplate Reader (12)](https://i0.wp.com/scv10mr-cdnpre-p-cus-00.azureedge.net/-/media/images/products/fluorometers-luminometers-multimode-readers/multimode-readers/glomax-discover/gm3000-microplate-reader-luminescence-detection.jpg?rev=0abb1c270de74df792a65aac9741ef09&sc_lang=it-it)
- Filter paddles and automatic filter switching allow easy two-color multiplexing assays or kinetic studies
- Quick read-speeds for high efficiencies in your laboratory
- Compatible for third-party automation control and data export to LIMS
![GloMax® Discover Microplate Reader (13) GloMax® Discover Microplate Reader (13)](https://i0.wp.com/scv10mr-cdnpre-p-cus-00.azureedge.net/-/media/images/products/fluorometers-luminometers-multimode-readers/multimode-readers/glomax-discover/gm3000-luminescence-detection-multimode-plate-reader.jpg?rev=3cee10c1a52a435c807baf97119daf78&sc_lang=it-it)
- Plate mask (aperture control) for switching between 96-well and 384-well plates
- Low cross-talk between wells gives you better, more usable results
- Broad dynamic range of the instrument extends the linear range of your assay
![GloMax® Discover Microplate Reader (14) GloMax® Discover Microplate Reader (14)](https://i0.wp.com/scv10mr-cdnpre-p-cus-00.azureedge.net/-/media/images/products/fluorometers-luminometers-multimode-readers/multimode-readers/glomax-discover/gm3000-glomax-microplate-reader.jpg?rev=62807fb5f6db498cad035cc400c9967f&sc_lang=it-it)
- Designed to comply with FDA 21CFR Part 11 regulations
- Provides user authentication and authorization, data Integrity and protection, electronic signatures, and audit trails
- IQ/OQ service available
- Field-based service available
Accurate Results from Every Well
There are three ways that microplate readers can affect how much useful information you get from each plate. Poor sensitivity may cause you to miss low-level samples that could be the “hit” you are looking for. Letting the signal from bright wells spill into adjacent wells allows crosstalk to occur and skews your experimental results. And a narrow detection range limits the accuracy and reproducibility that your work requires. With the GloMax® plate readers, you can rest easy and have confidence in your results.
GloMax® microplate readers offer superior sensitivity and auto-gain adjustment letting you measure weak and strong signals on the same plate.
The masking design of GloMax® microplate readers means you can be confident that the results from each well are not skewed by signal from neighboring wells.
With the broad detection range of GloMax® microplate readers, you can measure signals ranging from high intensity to near physiological levels.
Streamline Your Workflow with Automation
GloMax® Discover integrates with many commercially available automated systems, including liquid handers, plate stackers and robotic arms to enable seamless workflows for high-throughput assay quantitation and screening.
Our built-in and compliant SiLA2 communication driver makes integration easy.
![GloMax® Discover Microplate Reader (18) GloMax® Discover Microplate Reader (18)](https://i0.wp.com/scv10mr-cdnpre-p-cus-00.azureedge.net/-/media/images/logos/silariuntenswithoutr.jpg?rev=b71438d1b575452ea044df1997cb0837&sc_lang=it-it)
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Microplate Reader Compliance for Your GxP Workflow
![GloMax® Discover Microplate Reader (20) GloMax® Discover Microplate Reader (20)](https://i0.wp.com/scv10mr-cdnpre-p-cus-00.azureedge.net/-/media/images/products/fluorometers-luminometers-multimode-readers/glomax-workflow-figure.jpg?rev=2f6ff8a883a7492db45fad8a89011f29&sc_lang=it-it)
Not sure if GloMax® Discover is the right plate reader for your lab?
Find the instrument that's right for your needs.Compare Plate Readers
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Service and Support
One Call Supports It All
Promega supplies both the reagents and the instrument, so one call to Promega answers any questions you may have about assay chemistries or instrument performance.
Contact Technical Services
Ensure Minimal Instrument Downtime
- Field Support and Loaner Programs
- Service Packages
- IQ and OQ Packages
Warranty and Service Agreements
- Backed by a one-year warranty.
- Additional warranty and service agreements are available.
- For more information contact Promega Technical Services
Instrument Service and Support
Instrument Registration
![GloMax® Discover Microplate Reader (22) GloMax® Discover Microplate Reader (22)](https://i0.wp.com/scv10mr-cdnpre-p-cus-00.azureedge.net/-/media/images/resources/figures/14100-14199/multiplate-reader-fluorometer-support.jpg?rev=82f7fd787e534ed098eba1030f3935fc&sc_lang=it-it)
Design Features
Instrument Specifications
Detection Modes | Luminescence, Fluorescence Intensity, UV-Visible Absorbance, Filtered Luminescence, BRET and FRET |
Sample Format | 6-, 12-, 24-, 48-, 96- and 384-well plates |
Tablet PC | Windows® 8.1 or 10 Tablet PC with USB connection to instrument |
Read Speed | 96-well plate: less than 1 minute; 384-well plate: less than 3 minutes |
Automation Compatibility | Hardware and software accessible to third-party hardware/software control, including LIMS. |
Dimensions | 18.5in (46.9cm) width 19.5in (46.5cm) depth 10in (25.4cm) height without Tablet and PC mounted 16in (35.5cm) height with Tablet and PC mounted |
Weight | Approximately 60lb (27kg) |
Power Requirements | 120VA, 50/60HZ |
Warranty | 1-year parts and labor warranty included |
Regulatory Compliance | For Research Use Only. Not for use in Diagnostic Procedures |
Luminescence Module Specifications
Detector | Top-reading, head-on photon counting photomultiplier tube (PMT) |
Wavelength Range | 350–700nm |
Detection Limit | 3 × 10–21moles of luciferase |
Linear Dynamic Range | 9 logs |
Cross-talk | Less than 3 × 10–5(white, 96-well plate, Corning 3912) |
Filtered Luminescence | Built-in filter paddle |
Fluorescence Module Specifications
Detector | PIN-photodiode |
Light Source | Wavelength-matched LED |
Read Position | Top reading |
Wavelengths selection | Filter module with 5 standard excitation and emission filters. Empty filter positions are available for custom excitation and emission wavelengths. |
Wavelengths included | UV (Ex: 365nm, Em: 415–445nm) Blue (Ex: 475nm, Em: 500–550nm) Green (Ex: 520nm, Em: 580–640nm) Red (Ex: 627nm, Em: 660–720nm) AFC (Ex: 405nm, Em: 495–505nm) |
Detection Limit | 2fmol fluorescence dye/200µl |
Linear Dynamic Range | >6 logs (assay-dependent) |
UV-Visible Absorbance Module Specifications
Detector | Top-reading, head-on photon counting photomultiplier tube (PMT) |
Light Source | Xenon flash lamp |
Spectra Range | 200–600nm |
Filter Wheel | 9 absorbance filters included |
Wavelengths included | 230, 260, 280, 320, 405, 450, 490, 560 and 600nm 10nm band pass |
Detection Limit | 0.1 O.D. |
Dynamic Range | 0–4.0 O.D. |
Injector System Specifications
Number of injectors (optional) | Two injectors |
Dispense Volume Range | 5–200µl in 1µl increments |
Plate Compatibility | 6-, 12-, 24-, 48- and 96-well plates |
Injection Speed | 20–500µl per second |
Waste Collection Tray Volume | Approximately 50ml |
Void Volume | 500µl |
Heating System Specifications
Temperature Range | Ambient to 45°C |
Shaker System Specifications
Shaking Pattern | Linear or orbital patterns |
Shaking Intensity | 100–500 cycles/minute |
PC Requirements
Operating System | Windows® 8.1 or 10 Professional version, 64-bit, with USB connection to instrument |
RAM | 4GB |
Disk Space | 64GB |
Other Requirements | Microsoft.NET 4.6.1 Framework or newer (full version) |
Available Separately
Product | Catalog # |
---|---|
Luminometer Light Plate | E6531 |
Bar Code Reader | AS3200 |
USB Ethernet Adapter | AS8403 |
GloMax® Discover Empty Luminescence Filter Paddle | GM3011 |
GloMax® Discover Empty Fluorescence Filter Paddle | GM3012 |
GloMax® Discover Luminescence Filter Paddle | GM1090 |
GloMax® Discover Fluorescence Filter Paddle | GM1100 |
GloMax® Discover 96 Half-Position Aperture Assembly | GM1050 |
GloMax® Discover 96-Position Aperture Assembly | GM3040 |
GloMax® Discover 384-Position Aperture Assembly | GM3041 |
GloMax® Discover Aperture Plate | GM3042 |
GloMax® Dual Injectors with Pumps | GM3030 |
Inner and Outer Injector Tubing, Natural | GM3014 |
GloMax® Explorer Absorbance Module Upgrade | GM3520 |
GloMax® Discover-Explorer Sales Rental | E5301 |
GloMax® Discover or Explorer Installation Qualification | SA1104 |
GloMax® Discover or Explorer Operational Qualification | SA1105 |
GloMax® Discover or Explorer Installation and Operational Qualification | SA1106 |
GloMax® Discover Standard Service Agreement | SA4000 |
GloMax® Discover or Explorer Preventive Maintenance | SA4030 |
GloMax® Discover Premier Service Agreement | SA4002 |
GloMax® Discover Premier Warranty Upgrade | SA4001 |
Protocols
Complete Protocol
Portal Access Software Technical ManualPDF (6435 KB) – English
GloMax® Discover System Operating ManualPDF (30322 KB) – English
Quick Protocols
GloMax® Discover System Quick Start GuidePDF (3036 KB) – English
GloMax Discover System Creating a New Protocol FB166PDF (450 KB) – English
Video Protocols
Specifications
SDS
Search for SDS
Certificate of Analysis
Search by lot number
Use Restrictions
For Research Use Only. Not for Use in Diagnostic Procedures.
Storage Conditions
Patents and Disclaimers
European Pat. No. 2972400 and Japanese Pat. No. 6324485.
Resources
Articles
- Measuring Blockade of Immune Checkpoint Targets with Promega Bioassays and GloMax® Discover
- Multiplexing with NanoDLR and CellTiter-Fluor Assays
- Measuring the ADCC Reporter Bioassay Complete Kit (WIL2-S) Signal on the GloMax® Discover System
- Lumit® Cytokine Assays: Interpolating Data with the GloMax® Discover
Citations
-
β-Arrestin1 and 2 differentially regulate PACAP-induced PAC1 receptor signaling and trafficking.
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2018 PLos ONE - See all citations
Software and Firmware
- GloMax® Discover
- GloMax® Systems Preloaded Protocols
Other
- GloMax® Application Notes
- Overview of the GloMax® Analysis Software
- How To Export Templates and Results Using the GloMax® Analysis Software
- How To Edit a Graph Using the GloMax® Analysis Software
- How To Create an Analysis Template Using the GloMax® Analysis Software
- Measuring BRET Assays on the GloMax® Discover System
- Replacing Injector Tubing on GloMax Discover or Explorer Microplate Reader
- GloMax® Access Panel Installation Video
- GloMax® Access Panel Removal Video